Page 16 - El Tejano January 2018
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El Tejano   Magazine
                 ®
                     Two Pilot Clinical Studies Show Promising Results: AHCC Mushroom
                           Extract May Eradicate Recurrent HPV Infections in Women


          (NAPSI)—Two clinical studies conducted at McGovern      acylated alpha-1,4-glucans, AHCC has been the subject of
          Medical School at The University of Texas Health Science   over 60 Medline-indexed and more than 20 human studies.
          Center at Houston (UTHealth) showed that AHCC® mush-    Clinical research has shown that AHCC increases the num-
          room extract can clear infections in women with recurrent   ber and activity of natural killer (NK) cells, dendritic cells
          human papillomavirus (HPV). Results of the most recent   and specifi c cytokines that help the body fi ght off  infections
          study were presented at the 14th International Conference   and block growth of abnormal cells. The compound’s mode
          of the Society for Integrative Oncology held in Chicago on   of action has been shown to be the stimulation of TLR-2
          November 12−14, 2017.                                   and TLR-4 receptors in the gut and its function as a prebi-
                                                                  otic, nourishing the benefi cial colonic and intestinal bacte-
          The objective of the two studies was to determine whether   ria. AHCC has been widely used in Japan for over 30 years
          AHCC could eradicate an HPV infec-                                      and in the U.S. for more than 15 years.
          tion in women at two diff erent daily                                    It is off ered as a dietary supplement
          supplementation amounts (AHCC 1                                         and is also available in higher potency
          gram or AHCC 3 grams) and to assess                                     as a prescription medical food.
          the necessary duration for AHCC thera-
          py to be eff ective.                                                     AHCC Research Association

          The fi rst pilot study enrolled 10 women                                 The mission of the AHCC Research
          with persistent high-risk HPV infection                                 Association is to increase public aware-
          taking 3 grams of AHCC once daily                                       ness of AHCC in integrative medicine,
          from fi ve weeks up to six months.                                       educate consumers and doctors on
          Half of the subjects who stayed on    Scientists have found a way      AHCC’s preventative and therapeutic
          the protocol for four months showed a   to use a mushroom extract to   benefi ts, and support research studies
          complete eradication of the HPV virus.   help women infected with HPV.  on AHCC. For more information, please
          “Eradication” means that they cleared                                  visit www.ahccresearch.org.
          the infection by the end of the supplementation period and
          remained infection-free when tested two months post-sup-  Human Papillomavirus (HPV)
          plementation.
                                                                  The human papillomavirus (HPV) is a virus that has
          The second study, which looked at the effi  cacy of AHCC   been detected in more than 99 percent of cervical cancer
          at the 1-gram dose, tracked 10 women with persistent,   patients. According to the Centers for Disease Control
          high-risk HPV infections for up to a period of eight months.   and Prevention, several other cancers are related to HPV,
          The study observed that four of nine patients experienced   including 95 percent of anal cancers, 60 percent of oropha-
          eradication of the HPV infection by the end of the study   ryngeal cancers, 65 percent of vaginal cancers, 50 percent
          period. One patient was withdrawn from the study due to   of vulvar cancers and 35 percent of penile cancers.
          an unanticipated pregnancy and noncompliance with study
          protocol.                                               While most HPV infections are self-limiting and resolve
                                                                  without causing any symptoms, there is currently no ef-
          On average, it took the responders in the AHCC 1-gram   fective treatment for those that persist and that the body’s
          study longer to eradicate the HPV infection compared to   innate immune system cannot clear. According to Dr.
          duration of supplementation observed in the AHCC 3-gram   Judith Smith, “We test women for HPV, and if they have
          study. These fi ndings suggest that AHCC daily supplemen-  a persistent infection, there is nothing we can do for them
          tation successfully modulates the host immune system to   except watch and wait. With AHCC, we may be able to
          eff ectively eradicate persistent, high-risk HPV infections.   eliminate that terrible limbo when a woman is in between
          Since the AHCC 3-gram supplementation achieved results   HPV infection and a possible cancer diagnosis.”
          in shorter duration, it is the recommended supplementation   “HPV is associated with many life-threatening cancers,”
          dose for future evaluation and use for this research.   said Dr. Smith. “What we need is a safe, eff ective treatment
                                                                  for HPV before the cancer occurs.”
          The study was conducted by Dr. Judith Smith, the Direc-
          tor of Women’s Health Integrative Medicine Research     About Dr. Smith
          Program in the Department of Obstetrics, Gynecology &
          Reproductive Sciences at McGovern Medical School at the   Dr. Smith’s research focus is on the safe and eff ective use
          University of Texas.                                    of nutritional and herbal supplements with pharmacologic
                                                                  modalities as they relate to women’s health. Her current
          About AHCC                                              research involves cancer eradication of high-risk HPV
                                                                  infections in women with persistent HPV infection.
          AHCC is a compound derived from cultured mycelia of     For more information, please contact the AHCC Research
          Japanese lentinula edodes mushrooms. Standardized to    Association at info@ahccresearch.org.
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